Ti6Al4V Implants with Dense-Trabecular Bilayer Morphology for Bone Ingrowth: Synergy of Green Net Shaping and Sacrificial Templating

ACS Appl Bio Mater. 2024 Nov 18;7(11):7509-7521. doi: 10.1021/acsabm.4c01100. Epub 2024 Oct 23.

Abstract

Stress shielding in dental and orthopedic implants is a long-standing hurdle, and trabecular porous architecture to improve bone ingrowth is deemed to be a potential solution. Fabricating Ti6Al4V components with dense-porous bilayer structures is complicated with limited lab-scale and commercial success. Here, a green dough-forming technique with metal powders is successfully explored to develop heterogeneous structures with a monolith-like dense-porous interface. The porous region achieved 70% porosity with a 25 MPa compressive strength comparable to human cancellous bone. Due to its simplicity and versatility, this process is a promising solution for developing and mass-manufacturing customized designs for bone-related implants with improved bone ingrowth and osseointegration.

Keywords: Ti6Al4V dental implants; Widmanstätten structure; bimodal roughness; dense-porous bilayers; foam templating; green net shaping.

MeSH terms

  • Alloys* / chemistry
  • Biocompatible Materials / chemistry
  • Biocompatible Materials / pharmacology
  • Humans
  • Materials Testing*
  • Osseointegration / drug effects
  • Particle Size*
  • Porosity
  • Prostheses and Implants
  • Surface Properties
  • Titanium* / chemistry

Substances

  • Titanium
  • titanium alloy (TiAl6V4)
  • Alloys
  • Biocompatible Materials