Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis - A Report of 2 Cases

Fatemeh Mohaghegh; Zohre Khodashenas; Mina Saber; Haniyeh Sohrabi

doi:10.1159/000541695

Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis - A Report of 2 Cases

Case Rep Dermatol. 2024 Oct 24;16(1):226-233. doi: 10.1159/000541695. eCollection 2024 Jan-Dec.

Authors

Fatemeh Mohaghegh¹, Zohre Khodashenas², Mina Saber¹, Haniyeh Sohrabi³

Affiliations

¹ Department of Dermatology, Skin Diseases, and Leishmaniasis Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
² Department of Dermatology, Faculty of Medicine, Shahed University, Tehran, Iran.
³ School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Abstract

Introduction: Lichen planus (LP) is a chronic inflammatory dermatosis that causes plaques and itchy papules on the skin, as well as erosion and ulcers in the mucous membranes. LP is characterized by a dense dermal T-cell infiltration. Perieccrine inflammation can be seen in a variety of dermatoses, but genuine lymphocyte permeation of the secretory coil or lymphocytic syringotropism is a rare sign that is typically seen in mycosis fungoides.

Case presentation: In this study, we present 2 uncommon instances of lymphocytic syringotropism in LP. Histopathological examination revealed dense T-cell infiltration and lymphocytic involvement of eccrine glands, confirming syringotropism.

Conclusion: Lymphocytic syringotropism is an uncommon finding in LP. Its presence broadens the histopathological spectrum of LP and highlights the need to differentiate it from lymphoproliferative disorders like mycosis fungoides.

Keywords: Lichen planus; Mycosis fungoides; Syringotropic lichen planus.

Grants and funding

This research was conducted without any external funding or financial support. No grants, sponsorships, or third-party funding were involved in the execution or publication of this work.