Brief communication: comorbidities and aging in people living with HIV

AIDS Res Ther. 2024 Oct 26;21(1):77. doi: 10.1186/s12981-024-00667-8.

Abstract

The main objective of the study was to assess the occurrence of non-aids-related comorbidities typical of aging in people living with HIV diagnosis 20 years ago or more and under treatment with antiretroviral drugs for a long time. The associations between the same age group in people living with HIV with reported ART use 20 + years and people living with HIV with reported ART use between two and five years in relation to the risk of comorbidities studied, there was a predominance of metabolic alterations in the 50-60 and 60 + age groups (p < 0.003). The conclusion was that exists a higher risk of comorbidities associated with people living with HIV for more than 20 years, but the length of treatment did not necessarily influence this risk.

Keywords: Comorbidities; HIV; Premature aging; TCD4 + cells.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Aging*
  • Anti-HIV Agents / therapeutic use
  • Comorbidity*
  • Female
  • HIV Infections* / drug therapy
  • HIV Infections* / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Risk Factors

Substances

  • Anti-HIV Agents