Multicompartmentalized Micellar Structures by Gold Nanoparticles Grafted with Diblock-Copolymer Ligands

Chemphyschem. 2024 Dec 16;25(24):e202400747. doi: 10.1002/cphc.202400747. Epub 2024 Oct 28.

Abstract

We study the formation of hybrid polymer/inorganic colloidal particles with multicompartmentalized structure, comprising gold nanoparticles grafted with polystyrene-block-poly(methacrylic acid) (PSt-block-PMAA) diblock copolymer ligands, through experiments and molecular dynamics simulations. The PMAA blocks segregate into small satellite-like domains that are separated by the polystyrene spacer from the gold nanoparticle core. Dialysis against water leads to the re-configuration of the formed structures into unique, kinetically trapped pinned-micelle-decorated nanoparticles with internal structure.

Keywords: Block copolymers; Colloids; Gold nanoparticles; Multicompartmentalized structures; Surface-pinned micelles.