mRNA COVID-19 vaccinations are not associated with RVO development 21 days and 12 weeks after vaccination

Jacqueline K Shaia; Priya Shukla; Lee Jampol; Rishi P Singh

doi:10.1038/s41541-024-00983-0

mRNA COVID-19 vaccinations are not associated with RVO development 21 days and 12 weeks after vaccination

NPJ Vaccines. 2024 Oct 28;9(1):202. doi: 10.1038/s41541-024-00983-0.

Authors

Jacqueline K Shaia^{1

2}, Priya Shukla^{2

3}, Lee Jampol⁴, Rishi P Singh^{5

6}

Affiliations

¹ Case Western School of Medicine Department of Population and Quantitative Health Sciences, Cleveland, OH, USA.
² Center for Ophthalmic Bioinformatics Cleveland Clinic, Cleveland, OH, USA.
³ Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA.
⁴ Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
⁵ Center for Ophthalmic Bioinformatics Cleveland Clinic, Cleveland, OH, USA. [email protected].
⁶ Cleveland Clinic Martin Hospitals, Stuart , Florida , USA. [email protected].

Abstract

Case reports have speculated if COVID-19 vaccinations may be associated with retinal vascular occlusions (RVO). Specifically, previous literature speculated an increased risk of RVOs days to weeks after vaccination. After reviewing two recent analyses, mRNA COVID-19 vaccinations do not appear to increase the risk of RVOs at 3 and 12 weeks post-vaccination. Although both studies had different designs, mRNA vaccines do not appear to influence the risk of RVO development.

Publication types

Letter

Abstract

Publication types

Grants and funding