Intraocular acyclovir levels after subconjunctival and topical administration

Br J Ophthalmol. 1986 Feb;70(2):138-40. doi: 10.1136/bjo.70.2.138.

Abstract

Substantial levels of acyclovir were detected in the aqueous and vitreous of New Zealand rabbits at various time intervals following subconjunctival injection. Intravitreal penetration of acyclovir after topical application was poor.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acyclovir / administration & dosage
  • Acyclovir / metabolism*
  • Administration, Topical
  • Animals
  • Aqueous Humor / metabolism
  • Injections
  • Rabbits
  • Vitreous Body / metabolism

Substances

  • Acyclovir