Transileocolic Portal Vein Embolization Increases Remnant Liver Volume After Major Hepatectomy

In Vivo. 2024 Nov-Dec;38(6):2761-2766. doi: 10.21873/invivo.13755.

Abstract

Background/aim: Transileocolic portal vein embolization (TIPE) may reduce the risk of liver failure after massive hepatectomy. However, convincing evidence of its usefulness in this regard is yet to be reported. Therefore, this study aimed to investigate the use of TIPE after massive hepatectomy.

Patients and methods: Twelve patients who underwent TIPE were included. Pre- and postoperative liver volumetry was determined using a 3D simulator with computed tomography.

Results: After TIPE, the percent change in total liver volume was 104.0%±13.1% (p=0.08). Conversely, the percent increase in remnant liver volume (ml)/total liver volume (ml) and remnant liver volume (ml)/standard liver volume (ml) was 122.9%±18.6% (p<0.001) and 132.2%±19.6% (p<0.001), respectively. TIPE operation time was 125±84.6 min, with minimal blood loss in all cases. Postoperative hospitalization duration during TIPE was 4.5±2.6 days. No TIPE-related complications occurred in any patient.

Conclusion: TIPE is beneficial and safe when preoperative volumetry indicates that the remaining liver volume is inadequate and inoperable.

Keywords: Transileocolic portal vein embolization; hepatectomy; hepatomegaly; liver failure; massive liver resection; portal vein.

MeSH terms

  • Adult
  • Aged
  • Embolization, Therapeutic* / methods
  • Female
  • Hepatectomy* / methods
  • Humans
  • Liver Neoplasms / surgery
  • Liver Neoplasms / therapy
  • Liver* / diagnostic imaging
  • Liver* / pathology
  • Liver* / surgery
  • Male
  • Middle Aged
  • Organ Size
  • Portal Vein*
  • Tomography, X-Ray Computed
  • Treatment Outcome