Detection of Small Brain Metastases by 18F-Thretide PET/CT in Clear Cell Renal Cell Carcinoma

Xin Cheng; Guozhu Hou; Rong Zheng; Jingjing Zhang; Xuejuan Wang

doi:10.1097/RLU.0000000000005523

Detection of Small Brain Metastases by 18F-Thretide PET/CT in Clear Cell Renal Cell Carcinoma

Clin Nucl Med. 2024 Oct 30. doi: 10.1097/RLU.0000000000005523. Online ahead of print.

Authors

Xin Cheng¹, Guozhu Hou¹, Rong Zheng¹, Jingjing Zhang, Xuejuan Wang¹

Affiliation

¹ From the Department of Nuclear Medicine (PET-CT Center), National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

PMID: 39480242
DOI: 10.1097/RLU.0000000000005523

Abstract

A 46-year-old woman with a history of radical nephrectomy for clear cell renal cell carcinoma underwent 18F-FDG and 18F-Thretid (also known as Al18F-PSMA-BCH) PET/CT. Although the 18F-FDG PET/CT failed to detect any brain metastases, the 18F-Thretide PET/CT revealed 2 small metastases: one measuring 1.0 × 0.7 cm in the right cerebellum and the other measuring 0.4 cm in the right frontal lobe. These metastatic lesions were subsequently confirmed by brain MRI.