Protective effects of an mRNA vaccine candidate encoding H5HA clade 2.3.4.4b against the newly emerged dairy cattle H5N1 virus

Affiliations

• ¹ Pandemic Preparedness, Infection and Advanced Research Center, the University of Tokyo (UTOPIA), Tokyo, 108-8639, Japan; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, 53711, USA; Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, 108-8639, Japan.
• ² Pandemic Preparedness, Infection and Advanced Research Center, the University of Tokyo (UTOPIA), Tokyo, 108-8639, Japan; Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, 108-8639, Japan.
• ³ Vaccine Research Laboratories, Research Function, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, 134-8630, Japan.
• ⁴ Pandemic Preparedness, Infection and Advanced Research Center, the University of Tokyo (UTOPIA), Tokyo, 108-8639, Japan; The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, 162-8655, Japan.
• ⁵ Pandemic Preparedness, Infection and Advanced Research Center, the University of Tokyo (UTOPIA), Tokyo, 108-8639, Japan; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, 53711, USA; Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, 108-8639, Japan; The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, 162-8655, Japan. Electronic address: [email protected].