1 Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia (Kranzler). Mental Illness Research, Education and Clinical Center, Crescenz Veterans Affairs Medical Center, Philadelphia (Kranzler and Vickers-Smith). Department of Epidemiology, University of Kentucky College of Public Health, and Center on Drug and Alcohol Research, Department of Behavioral Science, University of Kentucky College of Medicine, Lexington (Vickers-Smith).