Heterotopic Ossification of the Elbow in a Patient With Cerebral Amyloid Angiopathy Following Intraparenchymal Hemorrhage: A Case Report

Cureus. 2024 Oct 1;16(10):e70643. doi: 10.7759/cureus.70643. eCollection 2024 Oct.

Abstract

Heterotopic ossification (HO) is a rare complication that may be initially discovered in the acute inpatient rehabilitation setting, caused by the abnormal formation of bone tissue in non-skeletal areas of the body. It may be caused by trauma or a neurological injury. When treating a patient with a history of neurological disease complicated by an acute event, treatment should be tailored to suit the patient's needs and to avoid further harm. This case explores the complexity of HO in a patient diagnosed with cerebral amyloid angiopathy following an intraparenchymal hemorrhage (IPH) and highlights the option of management with radiation therapy when non-steroidal anti-inflammatory drugs (NSAIDs) are contraindicated, not only to treat but also to prevent the progression of HO in this patient.

Keywords: cerebral amyloid angiopathy; hemorragic stroke; heterotopic ossification (ho); intraparenchymal hemorrhage; precision radiation therapy.

Publication types

  • Case Reports