Acquired von Willebrand Disease Associated With Severe Functional Mitral Regurgitation Improved by TEER

Yuki Obayashi; Shin Watanabe; Eri Toda Kato; Hiroki Shiomi; Chinatsu Yamada; Masayuki Fuki; Masahide Kawatou; Hisashi Sakaguchi; Kenji Minatoya; Koh Ono

doi:10.1016/j.jaccas.2024.102601

Acquired von Willebrand Disease Associated With Severe Functional Mitral Regurgitation Improved by TEER

JACC Case Rep. 2024 Oct 2;29(19):102601. doi: 10.1016/j.jaccas.2024.102601.

Authors

Affiliations

¹ Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
² Institute of Advancement of Clinical and Translational Science, Kyoto University Graduate School of Medicine, Kyoto, Japan.
³ Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Abstract

A 75-year-old man with a history of small intestinal angioectasia underwent transcatheter edge-to-edge repair for severe functional mitral regurgitation, resulting in recovery of large von Willebrand Factor multimers. This case highlights the potential of transcatheter edge-to-edge repair to manage both heart failure and acquired von Willebrand disease associated with functional mitral regurgitation.

Keywords: angioectasia; gastrointestinal bleeding; mitral regurgitation; transcatheter edge-to-edge repair; von Willebrand disease.

Publication types

Case Reports