Research on Perinatal Human Immunodeficiency Virus in Asia: Data on Treatment Outcomes and Emerging Co-Morbidities from the TREAT Asia Network

Clin Perinatol. 2024 Dec;51(4):911-923. doi: 10.1016/j.clp.2024.08.008. Epub 2024 Sep 10.

Abstract

Although new pediatric human immunodeficiency virus (HIV) infections have declined in the Asia-Pacific region, coverage of interventions to prevent vertical HIV transmission remains inconsistent. The TREAT Asia pediatric HIV cohort includes data from ∼7700 children and adolescents with HIV (90% perinatally acquired) who have been under care at 18 centers in six Asian countries. Research on their HIV treatment outcomes has been complemented by studies on coinfections and comorbidities. These studies have shown that greater attention is needed to support and sustain clinical and social outcomes as children with perinatal HIV age into adulthood and transition to adult HIV care.

Keywords: Adolescent; Asia; HIV; Pediatric; Perinatal; Treatment; Young adult; Youth.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Anti-HIV Agents / therapeutic use
  • Asia / epidemiology
  • Child
  • Child, Preschool
  • Coinfection / epidemiology
  • Comorbidity*
  • Female
  • HIV Infections* / drug therapy
  • HIV Infections* / epidemiology
  • Humans
  • Infant
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical* / prevention & control
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology
  • Treatment Outcome

Substances

  • Anti-HIV Agents