A Systematic Review and Quality Assessment of Cardiovascular Disease-Specific Health Related Quality of Life Instruments: Part II Psychometric Properties

Xue Li; Rui Li; Meixuan Li; Xu Hui; Jing Li; Liang Yao; Harriette Van Spall; Kun Zhao; Qiang Fu; Feng Xie

doi:10.1016/j.jval.2024.08.011

A Systematic Review and Quality Assessment of Cardiovascular Disease-Specific Health Related Quality of Life Instruments: Part II Psychometric Properties

Value Health. 2024 Oct 25:S1098-3015(24)06692-0. doi: 10.1016/j.jval.2024.08.011. Online ahead of print.

Authors

Xue Li¹, Rui Li², Meixuan Li³, Xu Hui³, Jing Li³, Liang Yao⁴, Harriette Van Spall⁵, Kun Zhao⁶, Qiang Fu⁷, Feng Xie⁸

Affiliations

¹ Department of Health Research Methods, Evidence and Impact, McMaster University, Canada, Ontario, Hamilton; Department of Health Technology Assessment, China National Health Development Research Centre, China, Beijing.
² Department of Health Technology Assessment, China National Health Development Research Centre, China, Beijing; Evidence Based Social Science Research Center/Health Technology Assessment Center, School of Public Health, Lanzhou University, China, Gansu, Lanzhou; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, China, Gansu, Lanzhou.
³ Evidence Based Social Science Research Center/Health Technology Assessment Center, School of Public Health, Lanzhou University, China, Gansu, Lanzhou; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, China, Gansu, Lanzhou.
⁴ Department of Health Research Methods, Evidence and Impact, McMaster University, Canada, Ontario, Hamilton.
⁵ Department of Health Research Methods, Evidence and Impact, McMaster University, Canada, Ontario, Hamilton; Department of Medicine, McMaster University, Canada, Ontario, Hamilton; Research Institute of St Joseph's and Population Health Research Institute, Canada, Ontario, Hamilton.
⁶ Department of Health Technology Assessment, China National Health Development Research Centre, China, Beijing; Vanke School of Public Health, Tsinghua University, China, Beijing.
⁷ Department of Health Technology Assessment, China National Health Development Research Centre, China, Beijing.
⁸ Department of Health Research Methods, Evidence and Impact, McMaster University, Canada, Ontario, Hamilton; Centre for Health Economics and Policy Analysis, McMaster University, Canada, Ontario, Hamilton. Electronic address: [email protected].

PMID: 39490978
DOI: 10.1016/j.jval.2024.08.011

Abstract

Objectives: Health-related Quality of Life (HRQoL) instruments for cardiovascular disease (CVD) have been commonly used to measure important patient-reported outcomes in clinical trials and practices. This study aimed at systematically identifying and evaluating the psychometric properties of CVD-specific HRQoL instruments.

Methods: We searched CINAHL, Embase, and PubMed from inception to January 20, 2022. Studies that reported psychometric properties of CVD-specific instruments were included. Two reviewers independently assessed the methodological quality using the Consensus-based Standards for the Selection of Health Measurement Instruments methods on evaluating measurement properties and quality of evidence. Seven psychometric properties, including structural validity, internal consistency, test-retest reliability, convergent validity, divergent validity, discriminative validity, and responsiveness, were evaluated.

Results: We identified 142 studies reporting psychometric properties of 40 instruments. 5 (12.5%) instruments demonstrated measurement properties with "sufficient" or "inconsistent" ratings. 16 (40.0%) instruments did not report any responsiveness evidence. Of the 40 instruments, 15 (37.5%) instruments were rated "sufficient" with high quality of evidence on internal consistency, 4 (10.0%) on structural validity, convergent validity and divergent validity and 3 (7.5%) on discriminative validity.

Conclusions: When measuring patient-reported outcomes in clinical trials or routine practice, it is important to choose instruments with established psychometric properties.

Keywords: Cardiovascular diseases; construct validity; health-related quality of life; patient-reported outcomes; psychometric properties; quality assessment; reliability; responsiveness.

Publication types

Review