Association of Objectively Measured Walking Speed with Incident Cardiovascular Diseases in Middle-Aged and Older Chinese Adults

Shuang Peng; Lei Yu; Yuhua Gao; Shan Dong; Yuhui Bai; Guojun Li; Changxue Liang; Zhuoyao Tian; Changsheng Lv; Fu Zhou; Yuan Wei; Ge Wang; Liangming Li; Guang Hao

doi:10.1016/j.hjc.2023.10.006

Association of Objectively Measured Walking Speed with Incident Cardiovascular Diseases in Middle-Aged and Older Chinese Adults

Hellenic J Cardiol. 2023 Oct 27:S1109-9666(23)00197-5. doi: 10.1016/j.hjc.2023.10.006. Online ahead of print.

Authors

Shuang Peng¹, Lei Yu², Yuhua Gao³, Shan Dong⁴, Yuhui Bai⁵, Guojun Li⁶, Changxue Liang⁵, Zhuoyao Tian⁵, Changsheng Lv⁶, Fu Zhou⁵, Yuan Wei⁵, Ge Wang⁷, Liangming Li⁸, Guang Hao⁹

Affiliations

¹ School of Sport and Health Sciences, Guangzhou Sport University, Guangzhou, Guangdong, 510500, China; Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou 510500, China. Electronic address: [email protected].
² Department of Pathophysiology, School of Medicine, Jinan University, Guangzhou, China.
³ School of Athletic Training, Guangzhou Sport University, Guangzhou 510500, China.
⁴ Guangzhou First People's Hospital, The Second Affiliated Hospital of South China University of Technology, Guangzhou, China.
⁵ Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou 510500, China.
⁶ School of Sport and Health Sciences, Guangzhou Sport University, Guangzhou, Guangdong, 510500, China.
⁷ Volleyball Teaching and Research Office of Sports Training Institute, Guangzhou Sport University, Guangzhou, China. Electronic address: [email protected].
⁸ School of Sport and Health Sciences, Guangzhou Sport University, Guangzhou, Guangdong, 510500, China; Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou 510500, China. Electronic address: [email protected].
⁹ Guangdong Provincial Engineering Research Center of Public Health Detection and Assessment, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China. Electronic address: [email protected].

PMID: 39491219
DOI: 10.1016/j.hjc.2023.10.006

Abstract

Objective: To evaluate the association between objectively measured walking speed and cardiovascular disease (CVD) risk in middle-aged and elderly Chinese adults.

Methods: A total of 3969 participants from the China Health and Retirement Longitudinal Study (CHARLS) were included in this study. Multilevel logistic and linear regression models (community-household-individual) were used to estimate the association between walking speed and the risk of CVD.

Results: A total of 1037 participants had a CVD event during the follow-up period, including 776 (19.6%) cases of cardiac disease and 353 (8.9%) cases of stroke. Participants who walked faster had a lower risk of CVD (Tertile 2: OR=0.80, 95%CI:0.67-0.97, P=0.022; Tertile 3: OR=0.73, 95%CI: 0.60-0.89, P=0.002). Further analysis showed that participants who walked faster also had a lower risk of cardiac disease and stroke (Cardiac disease: Tertile 2: OR=0.91, 95%CI:0.74-1.12, P=0.368; Tertile 3: OR=0.85, 95%CI: 0.68-1.07, P=0.161; Stroke: Tertile 2: OR=0.33, 95%CI:0.14-0.78, P=0.012; Tertile 3: OR=0.30, 95%CI: 0.11-0.82, P=0.019). The results were consistent in pre-specified subgroups by sex, age, and body mass index.

Conclusion: We found that faster objectively measured walking speed was significantly associated with a lower risk of CVD, especially stroke, in middle-aged and elderly Chinese people.

Keywords: cardiac disease; cardiovascular disease; cohort study; stroke; walking speed.