A dual-targeted trinity of antibody-peptide-drug delivery consortium to combat HER2+ tumor

Chem Commun (Camb). 2024 Nov 4. doi: 10.1039/d4cc05115g. Online ahead of print.

Abstract

We pioneered a dual-targeted trinity of antibody-peptide-drug delivery consortium to combat HER2+ tumors. This innovative approach leverages the self-assembly of peptides with high affinity to antibodies to create nanofibers for antibody encapsulation, offering a novel strategy in antibody drug delivery.