Cutaneous T-cell lymphoma: Consensus on diagnosis and management in Taiwan

Tai-Chung Huang; Chung-Hsing Chang; Pa-Fan Hsiao; Chao-Kai Hsu; Chien-Yio Lin; Chien-Shan Wu; Su-Peng Yeh; Tsen-Fang Tsai

doi:10.1016/j.jfma.2024.11.001

Cutaneous T-cell lymphoma: Consensus on diagnosis and management in Taiwan

J Formos Med Assoc. 2024 Nov 3:S0929-6646(24)00517-5. doi: 10.1016/j.jfma.2024.11.001. Online ahead of print.

Authors

Tai-Chung Huang¹, Chung-Hsing Chang², Pa-Fan Hsiao³, Chao-Kai Hsu⁴, Chien-Yio Lin⁵, Chien-Shan Wu⁶, Su-Peng Yeh⁷, Tsen-Fang Tsai⁸

Affiliations

¹ Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.
² Skin Institute, Department of Dermatology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan; Institute of Medical Sciences, College of Medicine, Tzu Chi University, Hualien, Taiwan.
³ Department of Dermatology, MacKay Memorial Hospital, Taipei, Taiwan; Department of Medicine, MacKay Medical College, New Taipei City, Taiwan; MacKay Junior College of Medicine, Nursing and Management, Taipei, Taiwan.
⁴ Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
⁵ Department of Dermatology, Chang Gung Memorial Hospital, Linkou and Taipei, Taiwan; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
⁶ Department of Dermatology, Pingtung Veterans General Hospital, Pingtung, Taiwan.
⁷ Division of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan; China Medical University, Taichung, Taiwan.
⁸ Department of Dermatology, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address: [email protected].

PMID: 39496538
DOI: 10.1016/j.jfma.2024.11.001

Abstract

Cutaneous T cell lymphomas (CTCLs), with mycosis fungoides (MF) and Sézary syndrome (SS) as the classic types, are the commonest group of primary cutaneous lymphomas. The diverse clinical manifestation and non-specific histologic findings of early lesions in CTCLs render diagnosis challenging. Treatment modalities also vary and include topical and oral medications, chemotherapy, phototherapy, and radiation therapies. Local dermatological, hemato-oncologic and radiotherapeutical experts in Taiwan convened meetings in 2023 to review and discuss the latest evidence and updates regarding diagnosis and management of CTCLs. A consensus was developed with the aim to raise awareness and understanding, provide practical guidance for early diagnosis and appropriate management, and ultimately optimize care to maximize benefits of patients.

Keywords: Cutaneous T cell lymphoma; Disease management; Mycosis fungoides; Skin neoplasms; Sézary syndrome.

Publication types

Review