AIntibody: an experimentally validated in silico antibody discovery design challenge
Nat Biotechnol
.
2024 Nov 4.
doi: 10.1038/s41587-024-02469-9.
Online ahead of print.
Authors
M Frank Erasmus
1
,
Laura Spector
2
,
Fortunato Ferrara
2
,
Roberto DiNiro
2
,
Thomas J Pohl
2
,
Katheryn Perea-Schmittle
2
,
Wei Wang
3
,
Peter M Tessier
4
,
Crystal Richardson
5
,
Laure Turner
5
,
Sumit Kumar
5
,
Daniel Bedinger
6
,
Pietro Sormanni
7
,
Monica L Fernández-Quintero
8
,
Andrew B Ward
8
,
Johannes R Loeffler
8
,
Olivia M Swanson
8
,
Charlotte M Deane
9
,
Matthew I J Raybould
9
,
Andreas Evers
10
,
Carolin Sellmann
10
,
Sharrol Bachas
11
,
Jeff Ruffolo
12
,
Horacio G Nastri
13
,
Karthik Ramesh
13
,
Jesper Sørensen
14
,
Rebecca Croasdale-Wood
15
,
Oliver Hijano
16
,
Camila Leal-Lopes
16
,
Melody Shahsavarian
17
,
Yu Qiu
16
,
Paolo Marcatili
18
,
Erik Vernet
18
,
Rahmad Akbar
18
,
Simon Friedensohn
19
,
Rick Wagner
20
,
Vinodh Babu Kurella
21
,
Shipra Malhotra
21
,
Satyendra Kumar
21
,
Patrick Kidger
22
,
Juan C Almagro
23
,
Eric Furfine
24
,
Marty Stanton
24
,
Christilyn P Graff
24
,
Santiago David Villalba
25
,
Florian Tomszak
25
,
Andre A R Teixeira
26
,
Elizabeth Hopkins
27
,
Molly Dovner
27
,
Sara D'Angelo
2
,
Andrew R M Bradbury
28
Affiliations
1
Specifica LLC, an IQVIA business, Santa Fe, USA.
[email protected]
.
2
Specifica LLC, an IQVIA business, Santa Fe, USA.
3
University of California, San Diego, USA.
4
University of Michigan, Ann Arbor, USA.
5
GENEWIZ from Azenta Life Sciences, South Plainfield, USA.
6
Carterra, Salt Lake City, USA.
7
University of Cambridge, Cambridge, UK.
8
Scripps Research Institute, San Diego, CA, USA.
9
University of Oxford, Oxford, UK.
10
Merck KGaA, Darmstadt, Germany.
11
Evolutionary Scale, San Francisco, USA.
12
Profluent Bio, Berkeley, USA.
13
Incyte, Inc, Wilmington, USA.
14
OpenEye, Cadence Molecular Sciences, Santa Fe, USA.
15
Astrazeneca, Cambridge, UK.
16
Sanofi, Inc, Cambridge, USA.
17
Eli Lilly, San Diego, USA.
18
Novo Nordisk, A/S, Bagsværd, Denmark.
19
Alloy Therapeutics, Basel, Switzerland.
20
Bonito Biosciences, Waltham, USA.
21
Takeda, Inc, Cambridge, USA.
22
Cradle Bio, Zürich, Switzerland.
23
GlobalBio, Inc., Cambridge, MA, USA.
24
Mosaic Biosciences, Boulder, USA.
25
Bayer AG, Leverkusen, Germany.
26
Institute for Protein Innovation, Boston, USA.
27
Sapidyne Instruments, Inc. & GmbH, Boise, USA.
28
Specifica LLC, an IQVIA business, Santa Fe, USA.
[email protected]
.
PMID:
39496931
DOI:
10.1038/s41587-024-02469-9
No abstract available
Publication types
Letter