Perspective: Raman spectroscopy for detection and management of diseases affecting the nervous system

John L Robertson; Amr Sayed Issa; Ryan S Senger

doi:10.3389/fvets.2024.1468326

Perspective: Raman spectroscopy for detection and management of diseases affecting the nervous system

Front Vet Sci. 2024 Oct 21:11:1468326. doi: 10.3389/fvets.2024.1468326. eCollection 2024.

Authors

John L Robertson^{1

2

3}, Amr Sayed Issa^{2

4}, Ryan S Senger^{2

4}

Affiliations

¹ Department of Biomedical Engineering, Virginia Tech, Blacksburg, VA, United States.
² Rametrix Technologies, Inc., Blacksburg, VA, United States.
³ Veterinary and Comparative Neurooncology Laboratory, Virginia Tech, Blacksburg, VA, United States.
⁴ Department of Biological Systems Engineering, Virginia Tech, Blacksburg, VA, United States.

Abstract

Raman spectroscopy (RS) is used increasingly for disease detection, including diseases of the nervous system (CNS). This Perspective presents RS basics and how it has been applied to disease detection. Research that focused on using a novel Raman-based technology-Rametrix^® Molecular Urinalysis (RMU)-for systemic disease detection is presented, demonstrated by an example of how the RS/RMU technology could be used for detection and management of diseases of the CNS in companion animals.

Keywords: Raman; brain; glioma; spectroscopy; tumors; urinalysis.

Grants and funding

The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.