Decreasing the Use of Cefdinir for Pediatric Urinary Tract Infections in a Rural Health Care System: A Quasi-experimental Study

J Pediatric Infect Dis Soc. 2024 Dec 30;13(12):643-646. doi: 10.1093/jpids/piae114.

Abstract

There are several antimicrobial options for treating urinary tract infections in children. Although cefdinir is commonly used, better options exist. We developed an intervention bundle to reduce the use of cefdinir in favor of cephalexin. The intervention bundle decreased cefdinir use by 19.1% (73% relative decrease) while the use of cephalexin increased by 19.8%.

Keywords: Antimicrobial Stewardship; Cefdinir; Cephalexin; Pediatric; Urinary Tract Infection.

MeSH terms

  • Anti-Bacterial Agents* / therapeutic use
  • Cefdinir* / therapeutic use
  • Cephalexin* / therapeutic use
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Male
  • Rural Population
  • Urinary Tract Infections* / drug therapy

Substances

  • Cefdinir
  • Anti-Bacterial Agents
  • Cephalexin