Advanced Endoscopic Imaging to Predict Clinical Outcomes in Inflammatory Bowel Disease

Udayakumar Navaneethan; Dennisdhilak Lourdusamy

doi:10.1016/j.giec.2024.05.001

Advanced Endoscopic Imaging to Predict Clinical Outcomes in Inflammatory Bowel Disease

Gastrointest Endosc Clin N Am. 2025 Jan;35(1):195-212. doi: 10.1016/j.giec.2024.05.001. Epub 2024 Jun 15.

Authors

Udayakumar Navaneethan¹, Dennisdhilak Lourdusamy²

Affiliations

¹ Center for Inflammatory Bowel Disease and Interventional Inflammatory Bowel Disease, Orlando Health, Orlando Health Digestive Health Institute, 22 West Underwood Street, Orlando, FL 32806, USA. Electronic address: [email protected].
² Department of Internal Medicine, Texas Health Presbyterian, 3000 I-35, Denton, TX 76201, USA.

PMID: 39510688
DOI: 10.1016/j.giec.2024.05.001

Abstract

Advanced endoscopic imaging including high-definition endoscopy, confocal laser endomicroscopy (CLE) and endocytoscopy (EC) serve as an adjunct to predict clinical outcomes in inflammatory bowel disease (IBD). CLE can identify gut barrier dysfunction which correlates with disease behavior and long-term disease outcome. EC allows the assessment of histologic activity. Future controlled studies are warranted to define a definite role of these novel technologies in the management of patients with IBD.

Keywords: Confocal laser endomicroscopy; Crohn’s disease; Endocytoscopy; Endoscopic imaging; Inflammatory bowel disease; Ulcerative colitis.

Publication types

Review

MeSH terms

Endoscopy, Gastrointestinal* / methods
Humans
Inflammatory Bowel Diseases* / diagnostic imaging
Microscopy, Confocal* / methods