Nutrition influences immunity: Diet and host-parasite interactions

Ioannis Eleftherianos; Wei Zhang; Gianluca Tettamanti; Lillia Daley; Amr Mohamed; David Stanley

doi:10.1016/j.ibmb.2024.104210

Nutrition influences immunity: Diet and host-parasite interactions

Insect Biochem Mol Biol. 2024 Dec:175:104210. doi: 10.1016/j.ibmb.2024.104210. Epub 2024 Nov 6.

Authors

Ioannis Eleftherianos¹, Wei Zhang², Gianluca Tettamanti³, Lillia Daley⁴, Amr Mohamed⁵, David Stanley⁶

Affiliations

¹ Infection and Innate Immunity Laboratory, Department of Biological Sciences, The George Washington University, Washington DC, 20052, USA. Electronic address: [email protected].
² National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering (Ministry of Education), Guizhou University, Guiyang, Huaxi District, 550025, China. Electronic address: [email protected].
³ Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy; Interuniversity Center for Studies on Bioinspired Agro-environmental Technology (BAT Center), University of Napoli Federico II, Portici, Italy. Electronic address: [email protected].
⁴ Infection and Innate Immunity Laboratory, Department of Biological Sciences, The George Washington University, Washington DC, 20052, USA.
⁵ Department of Entomology, Faculty of Science, Cairo University, Giza, 12613, Egypt. Electronic address: [email protected].
⁶ Biological Control of Insects Research Laboratory, USDA, Agricultural Research Service, Columbia, MO, 65203, USA. Electronic address: [email protected].

PMID: 39515668
DOI: 10.1016/j.ibmb.2024.104210

Abstract

Nutrition plays a major role in host immune responses and in pathogen resistance. Understanding the network that modulates the relationship between nutrition and immunity remains a challenge. Several pathways govern the direct effects of nutrition on host immunity and the indirect effects mediated by pathogen populations. We note host microbiota also influence the intricate relationships between nutrition and immunity. The purpose of this review is to discuss recent findings from nutritional research in relation to insect immunology. We outline the relationship between diet, immunity, disease, and microbiota in insects and emphasize the significance of utilizing an integrative, multifaceted approach to grasping the influence of nutrition on immunity.

Keywords: Co-infections; Immunity; Insulin signaling; Microbiota; Nutrition; Plant defenses.

Publication types

Review

MeSH terms

Animals
Diet*
Host-Parasite Interactions* / immunology
Insecta* / immunology
Insecta* / microbiology
Microbiota / immunology