A preclinical mouse model of hepatic metastasis to instruct effective treatment modalities

Arianna Pocaterra; Antonio Citro; Chiara Gnasso; Tamara Canu; Anna Tosi; Antonio Rosato; Antonio Esposito; Lorenzo Piemonti; Anna Mondino

doi:10.1016/bs.mcb.2024.07.008

A preclinical mouse model of hepatic metastasis to instruct effective treatment modalities

Methods Cell Biol. 2024:190:133-150. doi: 10.1016/bs.mcb.2024.07.008. Epub 2024 Sep 5.

Authors

Arianna Pocaterra¹, Antonio Citro², Chiara Gnasso³, Tamara Canu³, Anna Tosi⁴, Antonio Rosato⁵, Antonio Esposito⁶, Lorenzo Piemonti⁷, Anna Mondino⁸

Affiliations

¹ Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy. Electronic address: [email protected].
² Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute, Milan, Italy.
³ Experimental Imaging Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.
⁴ Immunology and Molecular Oncology Diagnostics, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.
⁵ Immunology and Molecular Oncology Diagnostics, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy; Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
⁶ Vita-Salute San Raffaele University, Milan, Italy; Experimental Imaging Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.
⁷ Vita-Salute San Raffaele University, Milan, Italy; Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute, Milan, Italy.
⁸ Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy.

PMID: 39515877
DOI: 10.1016/bs.mcb.2024.07.008

No abstract available

Keywords: Animal model; Chemotherapy; Hepatic metastasis; Immunotherapy; Magnetic resonance imaging; Multiplex immunofluorescence; Pancreatic ductal adenocarcinoma; Tumor microenvironment.