Consequences of hyposalivation in relation to cancer treatment and early management of radiation-induced caries: case reports

Br Dent J. 2024 Nov;237(9):705-709. doi: 10.1038/s41415-024-7894-6. Epub 2024 Nov 8.

Abstract

Given the prevalence of head and neck carcinoma and the salivary changes induced by the oral side effects of radiotherapy, such patients are at higher risk/susceptibility of developing dental caries. Radiation-caries is often under-treated in patients undergoing cervicofacial radiotherapy, yet these lesions can increase the risk of osteoradionecrosis due to necessary subsequent dental extractions. Moreover, xerostomia is accompanied by difficulties with speech, chewing and swallowing. The prevention and/or early management of radiation-induced carious lesions is essential in preventing oral complications and improving patients' quality of life. Based on a French case series, this paper proposes a protocol for the dental management of radiation-induced carious lesions.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma, Squamous Cell / radiotherapy
  • Dental Caries* / etiology
  • Dental Caries* / prevention & control
  • Female
  • Head and Neck Neoplasms / radiotherapy
  • Humans
  • Male
  • Middle Aged
  • Osteoradionecrosis / etiology
  • Osteoradionecrosis / therapy
  • Radiation Injuries / etiology
  • Radiation Injuries / therapy
  • Radiotherapy / adverse effects
  • Xerostomia* / etiology
  • Xerostomia* / therapy