Cerebrospinal Fluid Pressure Measurement and Infusion Studies Using Lumbar Puncture

Neuroimaging Clin N Am. 2025 Feb;35(1):27-40. doi: 10.1016/j.nic.2024.08.002. Epub 2024 Sep 10.

Abstract

Lumbar puncture provides an easy way of accessing the subarachnoid space. Measuring of the opening cerebrospinal fluid pressure is the most commonly used method of evaluating intracranial pressure but provides basic snapshot information only. Further insights into cerebrospinal fluid dynamics can be obtained through infusion studies, which rely on measurement of the degree of pressure change in response to addition of fluid volume into the subarachnoid space. The authors describe applications of these 2 techniques pertinent to a practicing neuroradiologist, who may be asked to assist with fluoroscopy-guided lumbar puncture in patients with increased body mass index or difficult spine anatomy.

Keywords: Cerebrospinal fluid; Hydrocephalus; Infusion test; Intracranial pressure; Lumbar puncture.

Publication types

  • Review

MeSH terms

  • Cerebrospinal Fluid Pressure* / physiology
  • Fluoroscopy / methods
  • Humans
  • Spinal Puncture* / methods
  • Subarachnoid Space / diagnostic imaging