Surgical Management of Non-ulcer, Nonneoplastic Gastric Perforations

Surg Clin North Am. 2025 Feb;105(1):187-200. doi: 10.1016/j.suc.2024.07.004. Epub 2024 Sep 26.

Abstract

Gastric perforation is a core emergency disease treated by the general surgeon. The majority are caused by peptic ulcer disease and neoplasms; however, other etiologies, such as iatrogenic injury and gastric ischemia, are prevalent enough to merit separate attention. While the authors can extrapolate from our knowledge of the treatment of ulcer and neoplastic perforations when treating the lesser known causes, there are nuanced differences in how they approach it. The recognition and treatment of non-ulcer, nonneoplasm gastric perforation will be the focus of this article.

Keywords: Doxycycline; Gastric perforation; Gastric volvulus; Iatrogenic gastric perforation; Ischemic gastritis.

Publication types

  • Review

MeSH terms

  • Humans
  • Stomach Diseases / diagnosis
  • Stomach Diseases / etiology
  • Stomach Diseases / surgery
  • Stomach Rupture* / diagnosis
  • Stomach Rupture* / etiology
  • Stomach Rupture* / surgery