A comprehensive review on the application of neural network model in microbial fermentation

Bioresour Technol. 2025 Jan:416:131801. doi: 10.1016/j.biortech.2024.131801. Epub 2024 Nov 10.

Abstract

The development of high-performance strains and the continuous breakthrough of strain screening technology also pose challenges to downstream fermentation optimization and scale-up. Therefore, neural network models are utilized to optimize the fermentation process to meet the goals of boosting yield or lowering cost, with the use of artificial intelligence technology in conjunction with the peculiarities of the fermentation process. High-performance strains' yield rise and fermentation process amplification will be sped up with the aid of neural network models. This paper offers a helpful review for anyone interested in state-of-the-art microbial fermentation processes, as it thoroughly reviews the application of neural network models in predicting fermentation yield, optimizing the fermentation process, and monitoring the fermentation process.

Keywords: Application; Fermentation; Microorganism; Neural network.

Publication types

  • Review

MeSH terms

  • Bacteria / metabolism
  • Fermentation*
  • Models, Biological
  • Neural Networks, Computer*