Cutaneous infection in an immunocompromised domestic cat caused by Setosphaeria turcica (Luttr.) Leonard & Suggs

Rev Argent Microbiol. 2024 Oct-Dec;56(4):390-393. doi: 10.1016/j.ram.2024.08.003. Epub 2024 Nov 12.

Abstract

This is the first report of a cutaneous infection in an immunocompromised domestic cat caused by Setosphaeria turcica. The investigation encompasses an assessment of its virulence factors and susceptibility to antifungal drugs. The isolated strain originated from a domestic cat displaying cutaneous lesions that tested positive for feline leukemia virus (FeLV) infection. Identification procedures employed both microscopic and molecular techniques, with molecular identification relying on ITS DNA sequencing. Enzymatic assays targeting lipase, phospholipase, protease, and keratinase yielded negative results, suggesting the prevalence of alternative virulence mechanisms. Successful treatment of the infection was achieved with itraconazole, and susceptibility testing confirmed its sensitivity to azoles and polyene antifungal drugs.

Keywords: Feline leukemia virus; Hongos patógenos; Micosis; Mycosis; Pathogenic fungi; Setosphaeria; Virus de la leucemia felina.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Antifungal Agents / therapeutic use
  • Ascomycota / isolation & purification
  • Cat Diseases* / drug therapy
  • Cat Diseases* / microbiology
  • Cats
  • Dermatomycoses* / drug therapy
  • Dermatomycoses* / microbiology
  • Dermatomycoses* / veterinary
  • Immunocompromised Host*
  • Itraconazole / therapeutic use

Substances

  • Antifungal Agents
  • Itraconazole