Albumin-bilirubin score in non-malignant liver and other diseases

World J Gastroenterol. 2024 Nov 7;30(41):4481-4483. doi: 10.3748/wjg.v30.i41.4481.

Abstract

The albumin-bilirubin (ALBI) score is derived from albumin and bilirubin levels. Currently, the ALBI score is widely used in various clinical settings. A recent article in the World Journal of Gastroenterology summarized the application of the ALBI score in various non-malignant liver diseases. The ALBI score has a predictive power that is superior or non-inferior to established numerous measures. This may be related to its contiguity, sensitivity, and inclusion of albumin. While we recognize the good results of the ALBI score in a number of diseases, the ALBI score also has limitations. Variation studies for population characteristics and other factors should be performed to validate the performance of ALBI. Further modifications or optimization of ALBI scores should be taken into account.

Keywords: Albumin-bilirubin score; Hepatitis; Liver cirrhosis; Liver injury; Liver transplantation.

MeSH terms

  • Bilirubin* / analysis
  • Bilirubin* / blood
  • Biomarkers / analysis
  • Biomarkers / blood
  • Humans
  • Liver / metabolism
  • Liver Diseases* / blood
  • Liver Diseases* / diagnosis
  • Liver Function Tests / methods
  • Predictive Value of Tests
  • Prognosis
  • Serum Albumin* / analysis
  • Serum Albumin* / metabolism
  • Serum Albumin, Human / analysis
  • Severity of Illness Index

Substances

  • Bilirubin
  • Serum Albumin
  • Biomarkers
  • Serum Albumin, Human