Outcome Factors for Women Undergoing Transcatheter Aortic Valve Replacement

Muhammad Asim Shabbir; Natalia Berry; Emily Perdoncin; Poonam Velagapudi

doi:10.1016/j.iccl.2024.08.009

Outcome Factors for Women Undergoing Transcatheter Aortic Valve Replacement

Interv Cardiol Clin. 2025 Jan;14(1):117-125. doi: 10.1016/j.iccl.2024.08.009. Epub 2024 Oct 3.

Authors

Muhammad Asim Shabbir¹, Natalia Berry², Emily Perdoncin³, Poonam Velagapudi⁴

Affiliations

¹ University of Nebraska Medical Center, 42 and Emile, Omaha, NE, USA. Electronic address: [email protected].
² Mid-Atlantic Permanente Medical Group, Mclean, VA, USA.
³ Kaiser Permanente San Francisco Medical Center, San Francisco, CA, USA.
⁴ University of Nebraska Medical Center, 42 and Emile, Omaha, NE, USA. Electronic address: https://twitter.com/pooh_velagapudi.

PMID: 39537283
DOI: 10.1016/j.iccl.2024.08.009

Abstract

Women with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR) have a higher burden of symptoms, are older at the time of the TAVR procedure, and have unique anatomic features that increase the periprocedural risk. However, long-term outcomes including mortality are favorable for women compared with men. Careful attention is needed in considering the vascular access route and choice of valve platform to mitigate complications. Large prospective trials dedicated to women undergoing TAVR are needed to investigate individual female-specific factors determining outcomes.

Keywords: Female; Gender differences; Outcomes; TAVR; Women.

Publication types

Review

MeSH terms

Aortic Valve / surgery
Aortic Valve Stenosis* / surgery
Female
Humans
Postoperative Complications / epidemiology
Postoperative Complications / prevention & control
Risk Factors
Sex Factors
Transcatheter Aortic Valve Replacement* / methods
Treatment Outcome