Nano-enhanced immunity: A bibliometric analysis of nanoparticles in vaccine adjuvant research

Hum Vaccin Immunother. 2024 Dec 31;20(1):2427464. doi: 10.1080/21645515.2024.2427464. Epub 2024 Nov 14.

Abstract

This study analyzed the growth, collaboration, citation trends, and emerging topics in nanoparticle-based vaccine and adjuvant research (NVAR) from 1977 to 2023, using data from the Scopus database. The field showed a steady growth rate of 7.53% per year. Leading researchers Jaafari, M.R. and Alving, C.R. contributed significantly to the field, with 24.22% of publications and 38.92% of total citations coming from the United States. International collaboration was very strong, particularly between the US, UK, Germany, China, and France. Key research topics include nanoparticles, immunotherapy, COVID-19, and vaccines with a focus on SARS-CoV-2 and malaria. Emerging topics include vaccine adjuvants, mRNA, and neutralizing antibodies. This study emphasizes the importance of ongoing collaboration and interdisciplinary efforts to advance the field of NVAR.

Keywords: COVID-19; Nanoparticle-based vaccine; adjuvant research; collaboration; immunotherapy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adjuvants, Vaccine
  • Antibodies, Neutralizing / immunology
  • Bibliometrics*
  • Biomedical Research
  • COVID-19 Vaccines / administration & dosage
  • COVID-19 Vaccines / immunology
  • Humans
  • Immunotherapy / methods
  • Malaria Vaccines / administration & dosage
  • Malaria Vaccines / immunology
  • Nanovaccines* / administration & dosage
  • Nanovaccines* / immunology

Substances

  • Adjuvants, Vaccine
  • Antibodies, Neutralizing
  • COVID-19 Vaccines
  • Nanovaccines
  • Malaria Vaccines

Grants and funding

The authors gratefully acknowledge funding from the Deanship of Graduate Studies and Scientific Research, Jazan University, Saudi Arabia, through Project Number: RG24-M024.