Single-nuclei transcriptomics reveals TBX5-dependent targets in a patient with Holt-Oram syndrome

J Clin Invest. 2024 Nov 14:e180670. doi: 10.1172/JCI180670. Online ahead of print.

Authors

Jeffrey D Steimle¹, Yi Zhao², Fansen Meng², Mikaela E Taylor¹, Diwakar Turaga³, Iki Adachi⁴, Xiao Li², James F Martin¹

Affiliations

¹ Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America.
² McGill Gene Editing Laboratory, Texas Heart Institute, Houston, United States of America.
³ Department of Pediatrics, Baylor College of Medicine, Houston, United States of America.
⁴ Department of Surgery, Baylor College of Medicine, Houston, United States of America.

PMID: 39541167
DOI: 10.1172/JCI180670

No abstract available

Keywords: Cardiology; Cardiovascular disease; Genetic diseases; Genetics; Molecular genetics.