Long Axial Field-of-View PET/CT: New Opportunities for Pediatric Imaging

Semin Nucl Med. 2025 Jan;55(1):76-85. doi: 10.1053/j.semnuclmed.2024.10.007. Epub 2024 Nov 13.

Abstract

The combined use of Positron Emission Tomography (PET) and Computed Tomography (CT) has become increasingly vital for diagnosing and managing oncological and infectious diseases in pediatric patients. The introduction of long axial field-of-view (LAFOV) PET/CT scanners, also known as "Total Body PET/CT," marks a significant advancement in nuclear medicine. This new technology enables faster pediatric imaging with substantially reduced radiation exposure and essentially eliminates the need for sedation, addressing previous critical concerns in pediatric imaging. This review will explore the applications and challenges of LAFOV PET/CT in pediatric imaging, highlight the benefits observed at two Danish hospitals, and evaluate its potential to transform the management of pediatric patients.

Publication types

  • Review

MeSH terms

  • Child
  • Humans
  • Pediatrics / methods
  • Positron Emission Tomography Computed Tomography* / methods