Pulmonary tuberculosis and renal amyloidosis: A rare entity in children

Trop Doct. 2024 Nov 15:494755241293181. doi: 10.1177/00494755241293181. Online ahead of print.

Abstract

Amyloidosis is a group of disorders with extracellular accumulation of autologous fibrillary insoluble proteins in various tissues and organs such as the kidneys, liver, spleen, heart, and gastrointestinal tract leading to impaired function. Renal amyloidosis is usually considered to be a progressive disease manifesting as nephrotic syndrome and renal insufficiency with tuberculosis being one of the most common causes in adults. However, the occurrence of similar associations is rarely described in children. We report a case of an 11-year old girl who presented with nephrotic syndrome and pulmonary tuberculosis and attained disease remission with successful treatment of tuberculosis.

Keywords: Tuberculosis; diagnosis; disease; immune; other; physiology; respiratory tract.