A Comparison of Subjective Symptoms of Two Types of Silicone Hydrogel One-Day Disposable Contact Lenses

Purpose: This study aimed to evaluate the comfort and discomfort of two types of soft contact lenses (SCLs) by comparing their quality of vision, fit, subjective dryness, and handling.

Methods: A total of 62 SCL wearers with contact lens (CL) discomfort were recruited. They were fitted with narafilcon A and verofilcon A for two weeks each by crossover. The comfort of the two types of SCLs was compared by having each participant answer a modified 5-Item Dry Eye Questionnaire (m-DEQ5, scores for vision, wearing comfort, and handling: the total score of the five items is a maximum of 25, higher being better) and modified Japanese version of the 8-item Contact Lens Dry Eye Questionnaire (m-J-CLDEQ-8: scores for discomfort and dry eye symptoms: the total score of the eight items is a maximum of 44; lower is better) survey forms. Results: Overall, the m-DEQ5 and m-J-CLDEQ-8 scores for the two SCLs of narafilcon A and verofilcon A were higher than the median of 3.0 points. Scores for 4 of 5 items and total scores in m-DEQ5 (18.7 ± 3.4 vs. 21.6 ± 2.5) were significantly higher and better in verofilcon A than in narafilcon A (p<0.01). Scores for 8 of 8 items and total scores on the m-J-CLDEQ-8 (15.2 ± 7.9 vs. 8.4 ± 4.9) were also significantly lower and better in verofilcon A than in narafilcon A (p<0.05).

Conclusion: Verofilcon A provided excellent vision, comfort, and ease of handling and was less likely to cause dry eye symptoms or eye discomfort. These results suggest that verofilcon A is an excellent option for patients with dry eye symptoms and CL discomfort.