Heart rate variability wrist-wearable biomarkers identify adverse posttraumatic neuropsychiatric sequelae after traumatic stress exposure

Affiliations

• ¹ Department of Anesthesiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27559, USA. Electronic address: [email protected].
• ² Institute for Trauma Recovery, Department of Anesthesiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27559, USA.
• ³ Departments of Psychiatry and Neurology, University of California San Francisco, San Francisco, CA, 94143, USA.
• ⁴ Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, 30332, USA; Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, 30332, USA.
• ⁵ Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, 30332, USA.
• ⁶ Institute for Trauma Recovery, Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27559, USA.
• ⁷ Institute for Trauma Recovery, UNC School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27559, USA.
• ⁸ Institute for Technology in Psychiatry, McLean Hospital, Belmont, MA, 02478, USA; Schizophrenia and Bipolar Disorder Research Program, McLean Hospital, Belmont, MA, 02478, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, 02115, USA.
• ⁹ Department of Epidemiology, Brown University, Providence, RI, 02930, USA; Department of Emergency Medicine, Brown University, Providence, RI, 02930, USA.
• ¹⁰ Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI, 48202, USA.
• ¹¹ Institute for Technology in Psychiatry, McLean Hospital, Belmont, MA, 02478, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, 02115, USA; The Many Brains Project, Belmont, MA, 02478, USA.
• ¹² Department of Psychology and Neuroscience & Department of Sociology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27559, USA.
• ¹³ Institute for Technology in Psychiatry, McLean Hospital, Belmont, MA, 02478, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, 02115, USA; Department of Psychiatry, McLean Hospital, Belmont, MA, 02478, USA.
• ¹⁴ Department of Emergency Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA.
• ¹⁵ Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
• ¹⁶ Department of Emergency Medicine, Henry Ford Health System, Detroit, MI, 48202, USA.
• ¹⁷ Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
• ¹⁸ Department of Emergency Medicine, University of Florida College of Medicine -Jacksonville, Jacksonville, FL, 32209, USA.
• ¹⁹ Department of Emergency Medicine, Cooper Medical School of Rowan University, Camden, NJ, 08103, USA.
• ²⁰ Department of Emergency Medicine, Ohio State University College of Medicine, Columbus, OH, 43210, USA; Ohio State University College of Nursing, Columbus, OH, 43210, USA.
• ²¹ Department of Emergency Medicine, Oakland University William Beaumont School of Medicine, Rochester, MI, 48309, USA.
• ²² Department of Emergency Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19121, USA.
• ²³ Department of Surgery, Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, 19104, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
• ²⁴ Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA; Department of Surgery, Division of Traumatology, Surgical Critical Care and Emergency Surgery, University of Pennsylvania, Philadelphia, PA, 19104, USA.
• ²⁵ Department of Emergency Medicine, Jefferson Einstein hospital, Jefferson Health, Philadelphia, PA, 19141, USA; Department of Emergency Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, 19107, USA.
• ²⁶ Department of Emergency Medicine, Wayne State University, Ascension St. John Hospital, Detroit, MI, 48202, USA.
• ²⁷ Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.
• ²⁸ Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA.
• ²⁹ Department of Emergency Medicine, Trinity Health-Ann Arbor, Ypsilanti, MI, 48197, USA.
• ³⁰ Department of Emergency Medicine, University of Massachusetts Medical School-Baystate, Springfield, MA, 01107, USA.
• ³¹ Department of Emergency Medicine, Wayne State University, Detroit Receiving Hospital, Detroit, MI, 48202, USA.
• ³² Department of Emergency Medicine, McGovern Medical School at UTHealth, Houston, TX, 77030, USA.
• ³³ Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA; Department of Emergency Medicine, Harvard Medical School, Boston, MA, 02115, USA.
• ³⁴ Department of Psychological Sciences, University of Missouri - St. Louis, St. Louis, MO, 63121, USA.
• ³⁵ Division of Biosciences, Ohio State University College of Dentistry, Columbus, OH, 43210, USA; Institute for Behavioral Medicine Research, OSU Wexner Medical Center, Columbus, OH, 43211, USA.
• ³⁶ Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA; Department of Internal Medicine-Rheumatology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.
• ³⁷ Department of Psychiatry, Harvard Medical School, Boston, MA, 02115, USA; Division of Depression and Anxiety, McLean Hospital, Belmont, MA, 02478, USA.
• ³⁸ Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, 02115, USA.
• ³⁹ Department of Health Care Policy, Harvard Medical School, Boston, MA, 02115, USA.
• ⁴⁰ Institute for Trauma Recovery, Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27559, USA; Department of Emergency Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27559, USA.