Introduction of dengue virus serotype 3 in the Afar Region, Ethiopia

Emerg Microbes Infect. 2024 Dec;13(1):2429653. doi: 10.1080/22221751.2024.2429653. Epub 2024 Nov 27.

Abstract

The genetic analysis of the Dengue virus circulating in Ethiopia's Afar region, in 2023, identified three distinct introductions with spatiotemporal clustering linked to genomes from Asia and Italy. These findings are crucial for enhancing prevention and control strategies, reinforcing the necessity to provide sustainable tools for genomic epidemiology in Africa.

Keywords: Ethiopia; Italy; dengue; genomic epidemiology; outbreak.

Publication types

  • Letter

MeSH terms

  • Dengue Virus* / classification
  • Dengue Virus* / genetics
  • Dengue Virus* / isolation & purification
  • Dengue* / epidemiology
  • Dengue* / virology
  • Ethiopia / epidemiology
  • Genome, Viral
  • Humans
  • Italy / epidemiology
  • Phylogeny*
  • Serogroup*

Grants and funding

This work was supported, in whole or in part, by the Bill and Melinda Gates Foundation [grants no. INV-034799 and INV-064464]. Under the grant conditions of the foundation, a Creative Commons Attribution 4.0 Generic License has already been assigned to the Author Accepted Manuscript version that might arise from this submission. Other sources of funding include the International Center for Genetic Engineering and Biotechnology (ICGEB CRP) to Ethiopia (CRP/ETH21-01) and PNRR – “GENESIS” – COC-1-2023-UNIPV – ID S1.P0002 (INF-ACT). The content and findings reported in this work are the sole responsibility of the researcher(s) involved and do not necessarily reflect the official positions or sentiments of the funding agencies that supported this project.