Methodologies and challenges in Arctic human health risk assessment: case studies and evaluation of current practices

Int J Circumpolar Health. 2024 Dec;83(1):2428471. doi: 10.1080/22423982.2024.2428471. Epub 2024 Nov 19.

Abstract

In Arctic populations, a primary route of exposure to contaminants is through the diet. The health risks associated with these exposures can be characterised by conducting human health risk assessments. However, while there is guidance from many international and national organisations, there are limited examples of human health risk assessment in the Arctic. The 2022 AMAP Human Health Assessment Report was the first AMAP report to describe, in one place, the utility of food-based, dietary intake-based and human tissue-based contaminant data in estimating risk. Here, we present available tools, case studies and challenges associated with conducting human health risk assessments in the Arctic. Future efforts in the Arctic should be able to use this information to best interpret human exposure to contaminants in a risk-based context.

Keywords: AMAP; Arctic; biomonitoring; contaminants; guidance value; human health; risk assessment.

MeSH terms

  • Arctic Regions
  • Diet
  • Environmental Exposure* / adverse effects
  • Environmental Exposure* / analysis
  • Food Contamination / analysis
  • Humans
  • Risk Assessment

Grants and funding

This research was supported by a grant from the Academy of Finland [grant number 356604]. The funding sources had no influence on the study design, collection, analysis, or interpretation of data, the writing of the report, or the decision to submit the article.