Systematic review and meta-analysis of the impact of infectious diseases consultation on outcomes of Staphylococcus aureus bacteremia in children

Haripriya Santhanam; Nirmal Muthukumarasamy; Mariana Kim Hsieh; Karen Brust; Melanie Wellington; Toshio Naito; Riley J Samuelson; Alexandre R Marra; Takaaki Kobayashi

doi:10.1017/ash.2024.450

Systematic review and meta-analysis of the impact of infectious diseases consultation on outcomes of Staphylococcus aureus bacteremia in children

Antimicrob Steward Healthc Epidemiol. 2024 Nov 11;4(1):e199. doi: 10.1017/ash.2024.450. eCollection 2024.

Authors

Haripriya Santhanam¹, Nirmal Muthukumarasamy², Mariana Kim Hsieh³, Karen Brust^{2

3}, Melanie Wellington^{3

4}, Toshio Naito⁵, Riley J Samuelson⁶, Alexandre R Marra^{3

7}, Takaaki Kobayashi^{2

3

8}

Affiliations

¹ Pediatrics, Eastern Iowa Health Center, Cedar Rapids, IA, USA.
² Department of Internal Medicine, Division of Infectious Diseases, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
³ The Program of Hospital Epidemiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
⁴ Department of Pediatrics, Division of Infectious Diseases, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
⁵ General Medicine, Juntendo University Hospital, Tokyo, Japan.
⁶ Hardin Library for the Health Sciences, University of Iowa Libraries, Iowa City, IA, USA.
⁷ Faculdade Israelita de Ciências da Saúde Albert Einstein, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
⁸ Department of Internal Medicine, Division of Infectious Diseases, University of Kentucky, Lexington, KY, USA.

Abstract

For adult patients with Staphylococcus aureus bacteremia (SAB), Infectious Diseases consultation (IDC) significantly lowers mortality and recurrence rate. Our systematic review and meta-analysis demonstrate that IDC is also associated with significantly lower mortality in children with SAB. Analysis of the impact of IDC on pediatric recurrence rates revealed moderate heterogeneity.