Residential Garden Produce Harvested Near a Fluorochemical Manufacturer in North Carolina Can Be An Important Fluoroether Exposure Pathway

J Agric Food Chem. 2024 Dec 4;72(48):26874-26883. doi: 10.1021/acs.jafc.4c06177. Epub 2024 Nov 20.

Abstract

Dietary intake can be an important exposure route to per- and polyfluoroalkyl substances (PFASs). Little is known about the bioaccumulation of emerging per- and polyfluoroalkyl ether acids (PFEAs) in garden produce from PFAS-impacted communities and the associated dietary exposure risk. In this study, 53 produce samples were collected from five residential gardens near a fluorochemical manufacturer. Summed PFAS concentrations ranged from 0.0026 to 38 ng/g wet weight of produce, and water-rich produce exhibited the highest PFAS levels. The PFAS signature was dominated by PFEAs, and hexafluoropropylene oxide-dimer acid (commonly known as GenX) was detected in 72% of samples. Based on average measured GenX concentrations, chronic-exposure daily limits were as low as 289 g produce/day for children (3-6 yr). This analysis does not consider other PFEAs that were present at higher concentrations, but for which reference doses were not available. This study revealed that consuming residential garden produce grown in PFAS-impacted communities can be an important exposure pathway.

Keywords: GenX chemicals; air emissions; fluoroethers; fruits; human exposure; vegetables.

MeSH terms

  • Child
  • Dietary Exposure / analysis
  • Fluorocarbons / analysis
  • Fluorocarbons / metabolism
  • Food Contamination* / analysis
  • Fruit / chemistry
  • Fruit / metabolism
  • Gardens
  • Humans
  • North Carolina
  • Vegetables / chemistry
  • Vegetables / metabolism

Substances

  • Fluorocarbons