Exploring the hidden world of RNA viruses with a transformer-based tool

So Nakagawa; Shoichi Sakaguchi

doi:10.1016/j.patter.2024.101095

Exploring the hidden world of RNA viruses with a transformer-based tool

Patterns (N Y). 2024 Nov 8;5(11):101095. doi: 10.1016/j.patter.2024.101095.

Authors

So Nakagawa^{1

2

3}, Shoichi Sakaguchi⁴

Affiliations

¹ Department of Molecular Life Science, Tokai University School of Medicine, Isehara, Japan.
² Division of Omics Sciences, Institute of Medical Sciences, Tokai University, Isehara, Japan.
³ Division of Interdisciplinary Merging of Health Research, Micro/Nano Technology Center, Tokai University, Hiratsuka, Japan.
⁴ Department of Microbiology and Infection Control, Faculty of Medicine, Osaka Medical and Pharmaceutical University, Takatsuki, Japan.

Abstract

Hou and He et al.¹ developed a new RNA virus identification tool named LucaProt, a transformer-based bioinformatics software using sequence and structural characteristics of RNA-dependent RNA polymerases (RdRPs), which are essential for almost all RNA viruses. LucaProt can identify RdRPs from highly diverse RNA viruses, unveiling the hidden RNA virosphere.

Publication types

News