While both in-center and home dialysis modalities have improved life expectancy for people with end-stage kidney disease and have served as a bridge to eventual kidney transplantation, kidney health care providers must be keenly aware of the potential complications associated with these therapies. The following questions aim to shed light on some of the more important potential physiological consequences and medical dilemmas associated with the three primary dialysis modalities including in-center hemodialysis, home hemodialysis, and peritoneal dialysis. Moreover, we hope to highlight that caring for those requiring dialytic therapy necessitates a significant breadth of understanding in other core internal medicine disciplines beyond nephrology itself, including cardiovascular, infectious, and musculoskeletal disease entities.
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