Characterization of pecan PEBP family genes and the potential regulation role of CiPEBP-like1 in fatty acid synthesis

Plant Sci. 2025 Feb:351:112326. doi: 10.1016/j.plantsci.2024.112326. Epub 2024 Nov 22.

Abstract

Phosphatidyl ethanolamine-binding protein (PEBP) plays important roles in plant growth and development. However, few studies have investigated the PEBP gene family in pecan (Carya illinoinensis), particularly the function of the PEBP-like subfamily. In this study, we identified 12 PEBP genes from the pecan genome and classified them into four subfamilies: MFT-like, FT-like, TFL1-like and PEBP-like. Multiple sequence alignment, gene structure, and conserved motif analyses indicated that pecan PEBP subfamily genes were highly conserved. Cis-element analysis revealed that many light responsive elements and plant hormone-responsive elements are found in CiPEBPs promoters. Additionally, RNA-seq and RT-qPCR showed that CiPEBP-like1 was highly expressed during kernel filling stage. GO and KEGG enrichment analysis further indicated that CiPEBP-like1 was involved in fatty acid biosynthesis and metabolism progress. Overexpression of CiPEBP-like1 led to earlier flowering and altered fatty acid composition in Arabidopsis seeds. RT-qPCR confirmed that CiPEBP-like1 promoted fatty acid synthesis by regulating the expression of key genes. Overall, this study contributes to a comprehensive understanding of the potential functions of the PEBP family genes and lay a foundation to modifying fatty acid composition in pecan kernel.

Keywords: CiPEBP-like1; PEBP family; fatty acid; overexpression; pecan.

MeSH terms

  • Arabidopsis / genetics
  • Arabidopsis / metabolism
  • Carya* / genetics
  • Carya* / metabolism
  • Fatty Acids* / biosynthesis
  • Fatty Acids* / metabolism
  • Gene Expression Regulation, Plant*
  • Genes, Plant
  • Multigene Family
  • Phosphatidylethanolamine Binding Protein / genetics
  • Phosphatidylethanolamine Binding Protein / metabolism
  • Phylogeny
  • Plant Proteins* / genetics
  • Plant Proteins* / metabolism

Substances

  • Plant Proteins
  • Fatty Acids
  • Phosphatidylethanolamine Binding Protein