Functional Recovery in a Child With Adrenoleukodystrophy Following Neuroregenerative Effects of Radio Electric Asymmetric Conveyer (REAC) Neuro-Regenerative (RGN-N) Treatment: A Detailed Case Report

Cureus. 2024 Nov 23;16(11):e74283. doi: 10.7759/cureus.74283. eCollection 2024 Nov.

Abstract

This case report describes the treatment of a 9-year-old boy with advanced adrenoleukodystrophy (ALD) who received radioelectric asymmetric conveyer (REAC) neuro-regenerative (RGN-N) therapy after hematopoietic stem cell transplantation (HSCT) failed to produce therapeutic benefits. ALD is a devastating neurodegenerative disorder for which limited treatment options exist, and interventions are often ineffective in advanced cases. Post-transplant, the patient's symptoms worsened until REAC RGN-N therapy was introduced. After treatment, notable improvements were observed in motor function, swallowing, spasticity, and overall quality of life. These results suggest that REAC RGN-N treatment may be an effective intervention to slow neurodegenerative progression and support recovery in ALD cases unresponsive to HSCT.

Keywords: hematopoietic stem cell transplantation (hsct); loes score; neuro regenerative treatment; neurobiological modulation; reac neuroregenerative therapy; x- linked adrenoleukodystrophy.

Publication types

  • Case Reports