PSMA-Guided Imaging and Therapy of Advanced Adenoid Cystic Carcinomas and Other Salivary Gland Carcinomas

Nils F Trautwein; Andreas Brendlin; Gerald Reischl; Moritz Mattke; Frank Paulsen; Hubert Loewenheim; Lars Zender; Christian la Fougère; Helmut Dittmann

doi:10.3390/cancers16223843

PSMA-Guided Imaging and Therapy of Advanced Adenoid Cystic Carcinomas and Other Salivary Gland Carcinomas

Cancers (Basel). 2024 Nov 15;16(22):3843. doi: 10.3390/cancers16223843.

Authors

Nils F Trautwein¹, Andreas Brendlin², Gerald Reischl^{3

4}, Moritz Mattke¹, Frank Paulsen⁵, Hubert Loewenheim⁶, Lars Zender^{4

7

8}, Christian la Fougère^{1

4

8}, Helmut Dittmann¹

Affiliations

¹ Department of Nuclear Medicine and Clinical Molecular Imaging, University of Tübingen, 72074 Tübingen, Germany.
² Department of Diagnostic and Interventional Radiology, University of Tübingen, 72074 Tübingen, Germany.
³ Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, 72076 Tübingen, Germany.
⁴ Cluster of Excellence iFIT (EXC 2180) "Image-Guided and Functionally Instructed Tumor Therapies", University of Tübingen, 72074 Tübingen, Germany.
⁵ Department of Radiation Oncology, University Hospital, 72076 Tuebingen, Germany.
⁶ Department of Otolaryngology-Head & Neck Surgery, University of Tübingen Medical Center, 72076 Tübingen, Germany.
⁷ Department of Medical Oncology and Pneumology (Internal Medicine VIII), University Hospital Tübingen, 72076 Tübingen, Germany.
⁸ German Cancer Consortium (DKTK), Partner Site Tübingen, 72076 Tübingen, Germany.

Abstract

SGCs are rare malignancies, accounting for less than 1% of all head and neck cancers [...].

Keywords: PET; PSMA-RLT; adenoid cystic carcinomas (ACCs); salivary gland carcinomas (SGCs).

Grants and funding

This research was supported by the medical faculty of the Eberhard Karls University Tübingen and the Ministry for Science, Research and the Arts Baden–Württemberg. This work was supported by the Clinician Scientist-Program Tübingen (525-0-0). The total-body PET/CT scanner was funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)—INST 37/1145-1 FUGG. Furthermore, this research was funded by the DFG under Germany’s Excellence Strategy—EXC 2180—390900677.