Post-radiation Angiosarcoma of the Vagina: A Case Report and Literature Review

Cureus. 2024 Oct 27;16(10):e72475. doi: 10.7759/cureus.72475. eCollection 2024 Oct.

Abstract

Angiosarcomas are rare and aggressive mesenchymal neoplasms that can be primary or secondary to other factors such as radiation exposure. They can occur anywhere in the body but are most commonly found on the skin. Post-radiation angiosarcoma of the vagina is a very rare neoplasm, with few cases reported in the literature. We report the case of an 83-year-old female patient who developed angiosarcoma of the vagina 14 years after receiving radiation therapy for rectal carcinoma. The patient was then treated with Taxol chemotherapy and showed an excellent response to treatment, with complete remission at four years post-treatment.

Keywords: post-radiation malignancy; radiation induced angiosarcoma; rare cancers; taxol; vaginal cuff.

Publication types

  • Case Reports