Chronic rhinosinusitis and asthma: epidemiology, pathophysiology, morbidity, treatment

Curr Opin Otolaryngol Head Neck Surg. 2025 Feb 1;33(1):1-6. doi: 10.1097/MOO.0000000000001022. Epub 2024 Nov 27.

Abstract

Purpose of review: Especially with the advent of biologics which have originally been prescribed primarily for pulmonary disease, the interconnections between asthma and chronic rhinosinusitis are becoming even more apparent. Biologics can now also be prescribed for chronic rhinosinusitis in some countries. But what is the epidemiology, pathophysiology and treatment of both diseases?

Recent findings: This review covers the epidemiology, pathophysiology, morbidity and treatment of both diseases. Specifically, this review highlights the interdependencies of both diseases and potential future treatment options.

Summary: This review aims to alert physicians to go beyond treating only one of the diseases, but rather to get a broader picture of the diseases and treatment options.

Publication types

  • Review

MeSH terms

  • Asthma* / epidemiology
  • Asthma* / physiopathology
  • Asthma* / therapy
  • Chronic Disease
  • Humans
  • Rhinitis* / epidemiology
  • Rhinitis* / physiopathology
  • Rhinitis* / therapy
  • Rhinosinusitis
  • Sinusitis* / epidemiology
  • Sinusitis* / physiopathology
  • Sinusitis* / therapy