The Novel HLA-DPB1*1327:01 Allele Identified by Next-Generation Sequencing in a Potential Haematopoietic Stem Cell Donor

HLA. 2024 Dec;104(6):e15786. doi: 10.1111/tan.15786.

He Zhao^{1

2

3}, Destinie Webster¹, Twyla Pearce¹, Mohamed Elemary^{4

5}, Ahmed Mostafa^{1

5}

¹ Histocompatibility and Immunogenetics Laboratory, St. Paul's Hospital, Saskatoon, Saskatchewan, Canada.
² College of Graduate and Postdoctoral Studies, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
³ Department of Obstetrics and Gynecology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, People's Republic of China.
⁴ Stem Cell Transplant and Cellular Therapy Program, Saskatoon Cancer Centre, Saskatoon, Saskatchewan, Canada.
⁵ College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

Abstract

The novel allele HLA-DPB1*1327:01 has a non-synonymous mutation difference compared with HLA-DPB1*04:01:01.

Keywords: HLA; HLA‐DPB1*1327:01; new allele; next‐generation sequencing.