Peliosis Hepatis Complicated by Scleroderma and Rapidly Progressing to Liver Failure

Intern Med. 2024;63(23):3171-3178. doi: 10.2169/internalmedicine.3508-24. Epub 2024 Dec 1.

Abstract

In November 2019, a 76-year-old woman was diagnosed with limited cutaneous scleroderma caused by Raynaud's phenomenon and skin hardening on the periphery of the extremities. In October 2022, blood tests and abdominal ultrasonography revealed liver dysfunction and multiple liver masses, respectively. In November 2022, a percutaneous liver mass biopsy revealed peliosis hepatitis, so the patient was referred to Kindai University Hospital, and signs of liver failure were observed. Considering her age, the patient was ineligible for liver transplantation, and she died in September 2023. Peliosis hepatis complicated by scleroderma has not been previously reported, so we report this as a valuable case.

Keywords: computed tomography; liver diseases; peliosis hepatis; scleroderma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Disease Progression
  • Fatal Outcome
  • Female
  • Humans
  • Liver Failure* / etiology
  • Peliosis Hepatis* / complications
  • Peliosis Hepatis* / diagnosis
  • Peliosis Hepatis* / diagnostic imaging
  • Scleroderma, Systemic / complications
  • Scleroderma, Systemic / diagnosis