Plasmapheresis as an Ischaemic Stroke Treatment: A Rare Case of Acquired Thrombotic Thrombocytopenic Purpura

Cureus. 2024 Oct 31;16(10):e72762. doi: 10.7759/cureus.72762. eCollection 2024 Oct.

Abstract

Acquired thrombotic thrombocytopenic purpura (acquired TTP) is a rare clinical syndrome caused by a decreased ADAMST13 activity, leading to systemic microvascular thrombotic events, with high mortality rates when the diagnosis and treatment are delayed. The authors report an acquired TTP in a patient with cerebrovascular disease. The aim is to emphasize the importance of considering atypical acquired TTP clinical presentations in order to optimize diagnostic and treatment approaches, minimize possible sequels, and improve the prognosis.

Keywords: acquired thrombotic thrombocytopenic purpura; adamts13 activity; plasmapheresis; stroke; thrombotic microangiopathy.

Publication types

  • Case Reports